Other than taking away from lean angle, I haven't heard anything else. I have been asking around cause even a ninja 250R in too tall for my SO. Also talk to Spencer's seats. He should be able to shave a some off your seat so you won't have to lower your bike that much.
2005 Honda 919
If you bite the hand that feeds you, it won't taste as good as the food you were fed.
I lowered Gin's 599 to fit her short stature. Raised the front forks 15mm, which is supposedly the safe limit without affecting handling adversely. Set the rear spring on its lowest (softest) setting, and had about 1.5" shaved off the seat by Spencer's seat mods. The bike rides fine, handles well, it's very low for me now but fits her much better.