There is no reason a clean, dry, properly adjusted modern O-ring chain would need in additional service during a 2,000 mile trip. Just the common sense stuff like checking tension now and then.
But...lube it up with something sticky that will collect road sand, and it will start the grinding process immediately.
As a machinist.... I cringe at the thought of taking a nice clean, dry, rolling mechanism like a chain and sprockets....thowing oil on them, then throwing a handful of sand on them. Can't think of a better way to accelerate wear, force dirt into seals, and make noise.
All the geezer hysteria about chain lube etc. is due to the 50 years of motorcycle chains BEFORE o-ring chains existed. (and I AM a geezer).
I would hop on my bike right now and do a 2,000 mile trip without the slightest concern for my chain. How many modern o-ring chains have you seen fail?