I just did this, but from central pa to niagara. I had to cut out toronto and a couple of the state parks and roads, cause it was my first big trip and idk wtf i'm doing haha.
I've been fiddling with pictures trying to clean up my cell phone shots, i'll have to get them up.
Check out Letchworth state park. I had to cut that out but i'm contemplating hitting it up on another trip. (google maps it and click explore). It looks awesome. Kinzau Bridge in PA was really cool. Lake Chautauqua was pretty. I would have rather spent more time riding in the allegany region than see lake Chautauqua tho. if you go that way i think they are doing construction on 430. the lakeview hotel/restaurant has wifi. rt 280 was fun.
Have you done niagara falls before?
canadian side was cool, i didn't see u.s. side. i failed to realize it wasn't just like a state park that you walk through at your leisure. it's time slot tickets, lines, and a lot of wasted time. But, i was behind Niagara falls, so that's pretty cool. If you don't care about that, i'd say go down to the parking section by the tours, slide around the barricade and park between the cars. walk along the river to horseshoe falls, and along the sidewalk till you feel like turning back, grab a coffee/bathroom or w/e at the tourist trap place then head up niagara parkway. once you're sorta away from the tourists pretend the signs are in mph, it's pretty fun road then
followed by a bunch of wineries and orchards.
Marion Brooks Natural Area is on a top 10 list of views in PA, something about a forest of birch trees. It got cut out so i can't say from experience. Hyner View was awesome though and the PA grand canyon. rt 44 is pretty boring except where it meets 144. we probably did the two most boring roads there, 120 and 44 (and my friend still managed to wreck). If you go to Hyner though, the gravel road connecting the park to 44 is fun.